Fourth, data from the Swedish Prescribed Drug Register do not include drugs for in-hospital use or drugs sold over-the-counter. Moreover, the register is incomplete as regards drugs used in nursing homes; occasionally in such residencies, medications from drug storerooms are dispensed without being registered in antibiotics for short-time use and temporary analgesics. Suicide and suicidal UNC0379 behavior are serious social and public problems in China and around the world, particularly in children and adolescents. Previous studies have also showed that suicide rate increased at the late teens and continued to rise until the early twenties. In addition, the prevalence of nonfatal suicidal behavior, including suicide thoughts, suicide plans, deliberate selfharm, and attempted suicide, are also common in 15�C24 year olds adolescents. In the United States, the average rate of adolescents reporting suicide attempts in the past one year is 6.4%, 12.4% reporting suicide plans, and 19.3% reporting suicide thoughts. In rural areas of China, the prevalence of suicide ideation, plans and attempts among adolescents are 19.3%, 10.5%, and 7.0%, respectively. Although only a small proportion of suicide attempters complete suicide eventually, suicide attempts are significant predictors and indicators of subsequent completed suicide. As a result, understanding youth suicide and suicide behavior and finding useful prevention strategies are extremely urgent. One of the most concerned risk factors for suicide and suicidal behavior is aggression/violence. First of all, they have a common basis in pathophysiology, the abnormal serotonergic system. For Nitroprusside disodium dihydrate example, lower level of cerebrospinal fluid 5-hydroxyindolacetic acid is not only associated with the increased risk of future suicide among adolescents, but also with the severity of lifetime aggression On the other hand, psychologically speaking, aggression is an important diathesis part of suicide behavior according to the stress-diathesis model proposed by John Mann. Individuals with this diathesis might be likely to experience more suicidal feelings and thoughts, and to be more impulsive. He also hypothesized that the risk for suicidal behavior was determined both by a psychiatric illness and by the diathesis, and the diathesis or trait-like predisposition was more important than the severity of the illness in predicting suicidal behavior. Previous studies in both high-risk individuals and school-based populations have found that trait aggression may act as a predictor of future suicide and elevate the risk for suicidal behavior. For example, Keilp JG et al��s study found that it was aggressiveness that held the most importance in predicting suicidal behavior when stratifying by borderline personality disorder, and that should be viewed as the ideal target for further research on suicidal behavior and for the clinical assessment of suicide risk.